Health Evidence Library
Curated research from trusted sources. Transparent. Cited. Always free.
5 records in the library
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Do omega-3 fatty acid supplements reduce symptoms of depression?
Appleton KM et al. · Cochrane Database of Systematic Reviews · 2021
The evidence is mixed. Some meta-analyses of randomized trials find a modest reduction in depression symptoms with omega-3 supplementation, particularly formulations high in EPA, while the most rigorous Cochrane systematic review found the evidence overall is low to moderate certainty and any benefit, if real, appears to be small.
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Does following a Mediterranean diet reduce the risk of dying from any cause?
Sofi F et al. · BMJ · 2008
Yes, with strong and consistent support. People who more closely follow a Mediterranean-style diet, rich in vegetables, fruit, whole grains, legumes, olive oil, and fish, with limited red and processed meat, have a lower risk of dying from any cause over long-term follow-up compared with people who follow it less closely.
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Does time-restricted eating improve metabolic health?
Sutton EF et al. · Cell Metabolism · 2018
Short-term evidence suggests time-restricted eating, especially eating earlier in the day within a 6- to 10-hour window, may improve insulin sensitivity, blood pressure, and some cardiometabolic markers, sometimes even without weight loss. Evidence for meaningful long-term weight loss specifically is more mixed, and larger, longer trials are still needed.
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Does vitamin D supplementation reduce the risk of acute respiratory infections?
Martineau AR et al. · The BMJ · 2017
Evidence suggests vitamin D supplementation modestly reduces the risk of acute respiratory tract infections overall, with the clearest benefit in people who are vitamin D deficient at baseline and in those taking daily or weekly doses rather than large infrequent bolus doses.
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Is high-intensity interval training (HIIT) better than moderate-intensity continuous training for cardiovascular health?
Weston KS et al. · British Journal of Sports Medicine · 2014
In people with existing cardiometabolic disease, HIIT produces a larger improvement in cardiorespiratory fitness (VO2peak) than moderate-intensity continuous training (MICT) of similar time commitment, with a comparable safety profile in supervised settings. For the general population without existing disease, evidence suggests both approaches meaningfully improve cardiovascular health, and consistency matters more than which one is chosen.